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By Jeremy Hanna
Contributing Sports Writer
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As the San Francisco 49ers enter into a must-win Week 12 game against the Green Bay Packers, it seems they'll be without yet another integral offensive piece.
According to Nick Wagoner of ESPN, the 49ers have officially designated left tackle Trent Williams as inactive with an ankle injury against the Packers.
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Williams will be sitting out alongside quarterback Brock Purdy, cornerback Charvarius Ward, defensive end Nick Bosa, wide receiver Jacob Cowing, defensive tackle Kevin Givens, and defensive tackle Khalil Davis.
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Needless to say, this will have a huge impact as San Francisco needs a big win over Green Bay today.
Williams is a key part of the 49ers offense and is considered by many to be one of the best offensive linemen in the NFL. Now, backup quarterback Brandon Allen is going to have an even more difficult time pulling out the win.
With Williams out, we'll likely see Jaylon Moore come in to pick up the slack.
Meanwhile, Green Bay will be missing cornerback Jaire Alexander, safety Kitan Oladapo, linebacker Edgerrin Cooper, and offensive lineman Jacob Monk.
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Williams first began his football career with the Oklahoma Sooners from 2006-09, where he was named a consensus All-American in 2009 and was first-team All-Big 12 in 2008 and 2009.
Williams was selected by the Washington Commanders with the fourth overall pick in the 2010 NFL Draft. He played with Washington for nine seasons. He was named to seven Pro Bowls in a row and second-team All-Pro in 2015.
In 2019, Williams had a surgical procedure to remove a cancerous growth from his head. After not being traded and not passing the physical to play in the 2019 season, Williams was granted permission to seek a trade.
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On April 25, 2020, Washington traded Williams to the 49ers for a fifth-round pick in the 2020 NFL Draft and a third-round pick in the 2021 NFL Draft.
Reunited with Kyle Shanahan, who used to be the offensive coordinator for Washington, Williams continued to show that he is one of the best in the business. Since the trade, he has been named to four more Pro Bowls and has been named first-team All-Pro for three consecutive seasons.
In total, Williams has been named to four All-Pro teams and 11 Pro Bowls. On Sept. 1, 2022, he was inducted into the Washington Commanders 90 Greatest.
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